RFdiffusion3 Documentation

RFdiffusion3 is a powerful protein design tool that operates on the atomic level to study ligand-protein interactions, create nucleic acid-protein interfaces, and design de novo enzymes. It is designed to be highly flexible and user-friendly, making it suitable for a wide range of applications in computational biology and biochemistry.

General

• Inference Calculation Basics
• RFdiffusion3 — Input Specification & Command-line arguments

Tutorials

• Protein-Protein Interface Design in RFdiffusion3

Examples

• RFdiffusion3 — Nucleic acid binder design examples
• RFdiffusion3 — Small molecule binder design examples
• RFdiffusion3 — Protein binder design examples
• Overview of Symmetry in RFD3
• RFdiffusion3 — Enzyme design examples